Probabilistic Study of Bone Remodeling Using Finite Element Analysis
More details
Hide details
Department of Mechanical Engineering Cleveland State University Cleveland, Ohio 44115 USA
Online publication date: 2013-09-06
Publication date: 2013-08-01
International Journal of Applied Mechanics and Engineering 2013;18(3):911-921
The dynamic bone remodeling process is a computationally challenging research area that struggles to understand the actual mechanisms. It has been observed that a mechanical stimulus in the bone greatly affects the remodeling process. A 3D finite element model of a femur is created and a probabilistic analysis is performed on the model. The probabilistic analysis measures the sensitivities of various parameters related to the material properties, geometric properties, and the three load cases defined as Single Leg Stance, Abduction, and Adduction. The sensitivity of each parameter is based on the calculated maximum mechanical stimulus and analyzed at various values of probabilities ranging from 0.001 to 0.999. The analysis showed that the parameters associated with the Single Leg Stance load case had the highest sensitivity with a probability of 0.99 and the angle of the force applied to the joint of the proximal femur had the overall highest sensitivity
Hazelwood S.J., Martin R.B., Rashid M.M. and Rodrigo J.J. (2001): A mechanistic model for internal bone remodeling exhibits different dynamic responses in disuse and overload. - Journal of Biomechanics, vol.34(3), pp.299-308.
Hazelwood S.J. and Castillo A.B. (2007): Simulated effects of marathon training on bone density, remodeling, and microdamage accumulation of the femur. - International Journal of Fatigue, vol.29, pp.1057-1064.
Journals System - logo
Scroll to top